Thermally Oxidized Dietary Fat Upregulates the Expression of Target Genes of PPARα in Rat Liver
نویسندگان
چکیده
منابع مشابه
Dietary oxidized fat prevents ethanol-induced triacylglycerol accumulation and increases expression of PPARalpha target genes in rat liver.
Alcoholic fatty liver results from an impaired fatty acid catabolism due to blockade of PPARalpha and increased lipogenesis due to activation of sterol regulatory element-binding protein (SREBP)-1c. Because both oxidized fats (OF) and conjugated linoleic acids (CLA) have been demonstrated in rats to activate hepatic PPARalpha, we tested the hypothesis that these fats are able to prevent ethanol...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2004
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/134.6.1375